Whole-genome resequencing of Pseudomonas aeruginosa PAO1 after anti-virulence treatments targeting iron uptake
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ABSTRACT: We carried out an experimental evolution in human serum as an ex-vivo model and screened evolved lines for the evolution of resistance phenotypes towards two anti-virulence treatments, gallium and flucytosine, which both target the iron scavenging pyoverdine of Pseudomonas aeruginosa (each at 2 different doses). We performed whole-genome sequencing of 16 evolved clones from the different treatment regimes .
INSTRUMENT(S): Illumina HiSeq 4000
ORGANISM(S): Pseudomonas aeruginosa
SUBMITTER: Stefan Wyder
PROVIDER: E-MTAB-6110 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
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