Transcriptome profiling of liver samples of C/EBPß ∆uORF mice

ABSTRACT: Synthesis of the metabolic transcription factor C/EBPβ-LIP is stimulated by mTORC1, which critically depends on a short upstream open reading frame (uORF) in the C/EBPβ-mRNA. We tested if that reduced C/EBPβ-LIP expression due to genetic ablation of the uORF delays the development of age-associated phenotypes in mice.

INSTRUMENT(S): Illumina HiSeq 2500

ORGANISM(S): Mus musculus

SUBMITTER: Victor Guryev 

PROVIDER: E-MTAB-6435 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress