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Breed gene expression differences in adult parent chicken with Affymetrix Chicken Gene Chip

ABSTRACT: Heritable epigenetic variation in wild and domesticated chickens. Original processed data are available in the archive: http://www.ebi.ac.uk/arrayexpress/files/E-MTAB-645/E-MTAB-645.additional.zip

ORGANISM(S): Gallus gallus

SUBMITTER: Daniel Natt

PROVIDER: E-MTAB-645 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Transmission of stress-induced learning impairment and associated brain gene expression from parents to offspring in chickens.

Lindqvist Christina C Janczak Andrew M AM Nätt Daniel D Nätt Daniel D Baranowska Izabella I Lindqvist Niclas N Wichman Anette A Lundeberg Joakim J Lindberg Johan J Torjesen Peter A PA Jensen Per P

PloS one 20070411 4

<h4>Background</h4>Stress influences many aspects of animal behaviour and is a major factor driving populations to adapt to changing living conditions, such as during domestication. Stress can affect offspring through non-genetic mechanisms, but recent research indicates that inherited epigenetic modifications of the genome could possibly also be involved.<h4>Methodology/principal findings</h4>Red junglefowl (RJF, ancestors of modern chickens) and domesticated White Leghorn (WL) chickens were ra ...[more]

PMID: 17426812

Publication: 1/6

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Breed gene expression differences in young offspring chicken with Affymetrix Chicken Gene Chip

Project description:Heritable epigenetic variation in wild and domesticated chickens. Original processed data are available in the archive: http://www.ebi.ac.uk/arrayexpress/files/E-MTAB-644/E-MTAB-644.additional.zip

2011-05-10 | E-MTAB-644 | biostudies-arrayexpress

Proteomic analysis of protein profile of blood serum of patients with autism children

Project description:A comparative panoramic mass spectrometric analysis of serum samples from three families with children with autistic disorders was carried out. The total number of examined samples was nine, including four control samples from healthy parents, and five samples from autistic children.

2016-11-01 | PXD005193 | Pride

Maternal western diet primes susceptibility to hepatic inflamation in adult male mouse offspring

Project description:Background & Aims: The influences of the maternal diet during gestation has been suggested to be involved in the development of different aspects of the metabolic syndrome. In our mouse model we characterised the role of maternal western diet in the development of non-alcoholic fatty liver disease (NAFLD) in the offspring. Methods: Female mice were fed either a western (W) or low-fat control (L) semi-synthetic diet before and during gestation and lactation. At weaning, male offspring were assigned either the W or the L diet, generating four experimental groups: WW, WL, LW and LL offspring. Biochemical, histological and epigenetic indicators were investigated at 29 weeks of age. Results: Male offspring exposed to prenatal western style diet and to a post-weaning W diet (WW) showed hepatomegaly combined with increased hepatic cholesterol and triglycerides accumulation, compared to LW offspring. This was associated with up-regulation of de novo lipid synthesis and dysregulation of beta oxidation and lipid storage. Elevated hepatic transaminases and increased expression of Tnfa, Cd11, Mcp1 and Tgfb underpin the severity of liver injury. Histological analysis supported the presence of steatohepatitis in the WW offspring. In addition alterations in DNA methylation in key metabolic genes (Ppara, Insig, Fasn) were detected. Conclusion: Maternal dietary fat intake during critical developmental phases programs susceptibility to liver disease in mouse offspring. This was mediated by shifts in lipid metabolism and inflammatory response. Long lasting epigenetic changes may underlie this dysregulation 4 groups of 6 male mouse were analysed , 1 experimental and 1 biological outlier was excluded , so n=6,5,5,6 in the 4 groups (LL,LW,WL,WW)

2014-01-21 | E-GEOD-44901 | biostudies-arrayexpress

Breed DNA-methylation in young offspring chicken with custom NimbleGen tiling array

Project description:To analyze DNA-methylation differences between two chicken breeds

2011-05-19 | E-MTAB-649 | biostudies-arrayexpress

Breed DNA-methylation in adult parent chicken with custom NimbleGen tiling array

Project description:To analyze DNA-methylation differences between two chicken breeds

2011-05-19 | E-MTAB-648 | biostudies-arrayexpress

Genome-wide DNA methylation profiling reveals epigenetic changes in the rat nucleus accumbens associated with cross-generational effects of adolescent THC exposure

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2015-06-19 | E-GEOD-69984 | biostudies-arrayexpress

Genome-wide copy number variation in Chinese schizophrenia trios

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Transcription profiling of chickens exposed to chronic unpredictable light or predictable light and their offspring

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2009-07-28 | E-MEXP-2268 | biostudies-arrayexpress

Expression data from WT (Columbia) and pifq (pif1pif3pif4pif5) mutant Arabidopsis seedlings

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| PRJNA493460 | ENA