Ontology highlight
ABSTRACT:
INSTRUMENT(S): Illumina HiSeq 2500
ORGANISM(S): Mus musculus
SUBMITTER: Leo Zeef
PROVIDER: E-MTAB-6474 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Strangward Patrick P Haley Michael J MJ Albornoz Manuel G MG Barrington Jack J Shaw Tovah T Dookie Rebecca R Zeef Leo L Baker Syed M SM Winter Emma E Tzeng Te-Chen TC Golenbock Douglas T DT Cruickshank Sheena M SM Allan Stuart M SM Craig Alister A Liew Foo Y FY Brough David D Couper Kevin N KN
Proceedings of the National Academy of Sciences of the United States of America 20180628 28
Cerebral malaria (CM) is a serious neurological complication caused by <i>Plasmodium falciparum</i> infection. Currently, the only treatment for CM is the provision of antimalarial drugs; however, such treatment by itself often fails to prevent death or development of neurological sequelae. To identify potential improved treatments for CM, we performed a nonbiased whole-brain transcriptomic time-course analysis of antimalarial drug chemotherapy of murine experimental CM (ECM). Bioinformatics ana ...[more]