A microarray meta-dataset of prostate cancer
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ABSTRACT: We present a meta-dataset comprising of a total of 237 samples including both primary tumors and tumor-free prostate tissues from six independent GEO datasets. To minimise inter-platform variation, only datasets generated from the GPL570 platform (Affymetrix Human Genome U133 Plus 2.0 Array) were processed to develop the meta-dataset. Using multiple open source R packages implemented in our previously developed bioinformatics pipeline, each dataset has been preprocessed with RMA normalisation, merged, and batch effect-corrected via Combat method. With increased sample size, the present meta-dataset serves an excellent 'discovery cohort' for discovering differentially expressed in diseased phenotype.
ORGANISM(S): Homo sapiens
SUBMITTER: Su Bin Lim
PROVIDER: E-MTAB-6694 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
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