Unknown,Transcriptomics,Genomics,Proteomics

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ChIP-chip of primary hippocampal neurons treated with lead against non-treated controls


ABSTRACT: The experiment was designed to investigate the regulatory landscape of H3K27me3, a histone methylation form, in the hippocampal neurons upon lead exposure. It reveals that the targeting pathways were altered and migrated throughout the genome, indicating that H3K27me3's sophisticated alterations are responsible for lead-led impairment of hippocampal neurons. Besides, the causes leading to its adaptive changes were figured out.

ORGANISM(S): Rattus norvegicus

SUBMITTER: Yi Xu 

PROVIDER: E-MTAB-6837 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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