RNA-seq of Arabidopsis thaliana wild-type and a putative chloroplast ribosome biogenesis mutant AtRsgA homozygous knockout
Ontology highlight
ABSTRACT:
INSTRUMENT(S): Illumina HiSeq 2500
ORGANISM(S): Arabidopsis thaliana
SUBMITTER: Dr. Marek Mutwil
PROVIDER: E-MTAB-6866 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Publications
AtRsgA from Arabidopsis thaliana is important for maturation of the small subunit of the chloroplast ribosome.
Janowski Marcin M Zoschke Reimo R Scharff Lars B LB Martinez Jaime Silvia S Ferrari Camilla C Proost Sebastian S Ng Wei Xiong Jonathan J Omranian Nooshin N Musialak-Lange Magdalena M Nikoloski Zoran Z Graf Alexander A Schöttler Mark A MA Sampathkumar Arun A Vaid Neha N Mutwil Marek M
The Plant journal : for cell and molecular biology 20180908 2
Plastid ribosomes are very similar in structure and function to the ribosomes of their bacterial ancestors. Since ribosome biogenesis is not thermodynamically favorable under biological conditions it requires the activity of many assembly factors. Here we have characterized a homolog of bacterial RsgA in Arabidopsis thaliana and show that it can complement the bacterial homolog. Functional characterization of a strong mutant in Arabidopsis revealed that the protein is essential for plant viabili ...[more]
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