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Effect of the IRE1a-XBP1 pathway inhibition during T helper 2 differentiation

ABSTRACT: The purpose of the study was to examine the role of the IRE1a-XBP1 pathway during Th2 lymphocyte activation and differentiation. In vitro Th2 cells were treated with 4μ8c, a drug that specifically inhibits IRE1a endonuclease activity, and transcriptomes were compared.

INSTRUMENT(S): Illumina HiSeq 2000

ORGANISM(S): Mus musculus

SUBMITTER: Jhuma Pramanik

PROVIDER: E-MTAB-6894 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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