Ontology highlight
ABSTRACT:
INSTRUMENT(S): Illumina HiSeq 1500
ORGANISM(S): Mus musculus
SUBMITTER: Kim Ravnskjaer
PROVIDER: E-MTAB-7054 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Marcher Ann-Britt AB Bendixen Sofie M SM Terkelsen Mike K MK Hohmann Sonja S SS Hansen Maria H MH Larsen Bjørk D BD Mandrup Susanne S Dimke Henrik H Detlefsen Sönke S Ravnskjaer Kim K
Scientific reports 20190220 1
Non-alcoholic steatohepatitis (NASH) signified by hepatic steatosis, inflammation, hepatocellular injury, and fibrosis is a growing cause of chronic liver disease, cirrhosis, and hepatocellular carcinoma. Hepatic fibrosis resulting from accumulation of extracellular matrix proteins secreted by hepatic myofibroblasts plays an important role in disease progression. Activated hepatic stellate cells (HSCs) have been identified as the primary source of myofibroblasts in animal models of hepatotoxic l ...[more]