Differential gene expression in mucosa of the small intestine and colon from germ-free, E.coli strains Nissle 1917 and O6K13 monoassociated, and conventionally reared mice

ABSTRACT: Commensal microbiota contribute to gut homeostasis and influence mucosal gene expression. We harvested mucosal lining of middle and distal part of the small intestine and colon from germ-free (GF) and gnotobiotic mice monocolonized either with the E.coli strain O6K13 (O) or Nissle 1917 strain (N). The expression profiles of the mucosa samples were compared to the corresponding tissue isolated from conventionally reared mice in order to disclose genes differentially expressed in response to the change in the intestinal microflora composition.

ORGANISM(S): Mus musculus

SUBMITTER: Vladimir Korinek 

PROVIDER: E-MTAB-7726 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress