Ontology highlight
ABSTRACT:
ORGANISM(S): Homo sapiens
SUBMITTER: Angela Bartley
PROVIDER: E-MTAB-813 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Clinical cancer research : an official journal of the American Association for Cancer Research 20110923 23
<h4>Purpose</h4>MicroRNAs are short noncoding RNAs that regulate gene expression and are over- or underexpressed in most tumors, including colorectal adenocarcinoma. MicroRNAs are potential biomarkers and therapeutic targets and agents, but limited information on microRNAome alterations during progression in the well-known adenoma-adenocarcinoma sequence is available to guide their usage.<h4>Experimental design</h4>We profiled 866 human microRNAs by microarray analysis in 69 matched specimens of ...[more]