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FloChIP's histone mark data obtained in multiplexing mode

ABSTRACT: By using FloChIP’s “sample multiplex” mode, we ChIPed in parallel 5 histone marks (H3K27ac, H3K4me3, H3K4me1 and H3K9me3), going from chromatin to sequencing-ready libraries, in just one day.

INSTRUMENT(S): NextSeq 500

ORGANISM(S): Homo sapiens

SUBMITTER: Riccardo Dainese

PROVIDER: E-MTAB-8551 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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FloChIP's histone mark data obtained in multiplexing mode

Project description:By using FloChIP’s “sample multiplex” mode, we ChIPed in parallel 5 histone marks (H3K27ac, H3K4me3, H3K27me3, H3K4me1 and H3K9me3), going from chromatin to sequencing-ready libraries, in just one day.

2020-06-26 | E-MTAB-7122 | biostudies-arrayexpress

FloChIP's decreasing cell number data obtained in multiplexing mode

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FloChIP's MEF2-A data obtained with high-throughput chip

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Mode-multiplexing deep-strong light-matter coupling.

Project description:Dressing electronic quantum states with virtual photons creates exotic effects ranging from vacuum-field modified transport to polaritonic chemistry, and squeezing or entanglement of modes. The established paradigm of cavity quantum electrodynamics maximizes the light-matter coupling strength ΩR/ωc , defined as the ratio of the vacuum Rabi frequency and the frequency of light, by resonant interactions. Yet, the finite oscillator strength of a single electronic excitation sets a natural limit to ΩR/ωc . Here, we enter a regime of record-strong light-matter interaction which exploits the cooperative dipole moments of multiple, highly non-resonant magnetoplasmon modes tailored by our metasurface. This creates an ultrabroadband spectrum of 20 polaritons spanning 6 optical octaves, calculated vacuum ground state populations exceeding 1 virtual excitation quantum, and coupling strengths equivalent to ΩR/ωc=3.19 . The extreme interaction drives strongly subcycle energy exchange between multiple bosonic vacuum modes akin to high-order nonlinearities, and entangles previously orthogonal electronic excitations solely via vacuum fluctuations.

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Mode-matching metasurfaces: coherent reconstruction and multiplexing of surface waves.

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Mode division multiplexing using an orbital angular momentum mode sorter and MIMO-DSP over a graded-index few-mode optical fibre.

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