Transcription profiling of mouse hippocampus, lung and liver for expression quanitative trait analysis
Ontology highlight
ABSTRACT:
ORGANISM(S): Mus musculus
SUBMITTER: Richard Mott
PROVIDER: E-MTAB-88 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Publications
High resolution mapping of expression QTLs in heterogeneous stock mice in multiple tissues.
Huang Guo-Jen GJ Shifman Sagiv S Valdar William W Johannesson Martina M Yalcin Binnaz B Taylor Martin S MS Taylor Jennifer M JM Mott Richard R Flint Jonathan J
Genome research 20090417 6
A proportion of the genetic variants underlying complex phenotypes do so through their effects on gene expression, so an important challenge in complex trait analysis is to discover the genetic basis for the variation in transcript abundance. So far, the potential of mapping both quantitative trait loci (QTLs) and expression quantitative trait loci (eQTLs) in rodents has been limited by the low mapping resolution inherent in crosses between inbred strains. We provide a megabase resolution map of ...[more]
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