BRAF paradox breakers PLX8394 and PLX7904 comparison to BRAF inhibitor PLX4720 effect on BRAF V600Ε mutant colorectal adenocarcinoma cells

ABSTRACT: Genomic analysis on RKO cells treated with PLX7904, PLX8394 and PLX4720 to reveal gene expression patterns. The goal is to investigate the potential of the novel BRAF inhibitors-paradox breakers to impede colorectal cancer cells proliferation, using human cell lines bearing the BRAFV600E mutation.

INSTRUMENT(S): BGISEQ-500

ORGANISM(S): Homo sapiens

SUBMITTER: Georgia Kontogianni 

PROVIDER: E-MTAB-9014 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress