Ontology highlight
ABSTRACT:
INSTRUMENT(S): Illumina HiSeq 4000
ORGANISM(S): Danio rerio
SUBMITTER: Sebastian Eilebrecht
PROVIDER: E-MTAB-9056 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Reinwald Hannes H König Azora A Ayobahan Steve U SU Alvincz Julia J Sipos Levente L Göckener Bernd B Böhle Gisela G Shomroni Orr O Hollert Henner H Salinas Gabriela G Schäfers Christoph C Eilebrecht Elke E Eilebrecht Sebastian S
The Science of the total environment 20201210
Endocrine disruption (ED) can trigger far-reaching effects on environmental populations, justifying a refusal of market approval for chemicals with ED properties. For the hazard assessment of ED effects on the thyroid system, regulatory decisions mostly rely on amphibian studies. Here, we used transcriptomics and proteomics for identifying molecular signatures of interference with thyroid hormone signaling preceding physiological effects in zebrafish embryos. For this, we analyzed the thyroid ho ...[more]