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Microarray of peripheral blood mononuclear cells from palindromic rheumatism patients during and between flares.

ABSTRACT: Aim: To assess the gene expression profiles of peripheral blood mononuclear cells obtained from palindromic rheumatism patients during flares and between flares. Samples were paired so we could assess the differences in gene expression profiles per a given patient during a flare and between flares. Method: PBMCs were extracted from whole blood and run on Illumina HT-12 v4 beadchips. The raw data from Illumina’s iScan software were read into R (version 3.4.4) and processed (background corrected, normalised and summarised) using the beadarray package (version 2.34.0). Linear models made using Limma (version 3.34.9) were used to assess differential expression of genes (DEGs).

ORGANISM(S): Homo sapiens

SUBMITTER: Shoaib Ajaib

PROVIDER: E-MTAB-9179 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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