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Galactosylceramide impact on male and female Cln3Δex7/8 mouse brain gene expression

ABSTRACT: The purpose of this study is to discern global expression programs embodying therapeutic targeting of CLN3 disease. Differential gene expression in Cln3Δex7/8 mouse brains was determined after intraperitoneal vehicle/Galactosylceramide (GalCer) injections, for 40 weeks, using GeneChip Mouse Genome 430 2.0 arrays. Differentially expressed genes among Cln3Δex7/8 mice and profiles modulated by GalCer treatment were functionally analyzed and topologically organized.

ORGANISM(S): Mus musculus

SUBMITTER: Joelle Makoukji

PROVIDER: E-MTAB-9232 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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