Multi-omic analysis resolves coordinated immune responses to mild, moderate and severe COVID-19

ABSTRACT: This study utilizes multi-omic biological data to perform deep immunophenotyping on the major immune cell classes in COVID-19 patients. 10X Genomics Chromium Single Cell Kits were used with Biolegend TotalSeq-C human antibodies to gather single-cell transcriptomic, surface protein, and TCR/BCR sequence information from 254 COVID-19 blood draws (a draw near diagnosis (-BL) and a draw a few days later (-AC)) and 16 healthy donors.

INSTRUMENT(S): Illumina NovaSeq 6000

ORGANISM(S): Homo sapiens

SUBMITTER: Daniel Chen 

PROVIDER: E-MTAB-9357 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress