RNA-seq of human donors with severe type 1 interferonopathy due to germline STAT2 gain-of-function
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ABSTRACT: Patients with type 1 interferonopathies due to mutations in one of 10 genes were recruited over the course of 4 years. All patients had raised levels of interferon stimulated genes as determined by qPCR. A transcriptome analysis was carried out to compare levels of interferon stimulated genes in the patient with a mutation in STAT2, compared to patients with mutations in other interferonopathy genes.
INSTRUMENT(S): Illumina HiSeq 4000
ORGANISM(S): Homo sapiens
SUBMITTER: Leo Zeef
PROVIDER: E-MTAB-9722 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
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