Unknown,Transcriptomics,Genomics,Proteomics

Dataset Information

0

Transcriptional profiling of the developmental gene whiA deletion mutant of Streptomyces venezuelae ATCC 10712 at 7 time points from 8 to 20 hours of growth.


ABSTRACT: WhiA is an unusual transcriptional regulator found in Streptomyces species related to eukaryotic homing endonucleases. It plays a central role in sporulation in these bacteria. The aim of this transcription profiling experiment was to measure genome wide transcript levels in the wild type and the whiA deletion mutant at 7 time points from 8 to 20 hours during the growth cycle of Streptomyces venezuelae.

INSTRUMENT(S): i686

ORGANISM(S): Streptomyces venezuelae

SUBMITTER: Matthew Bush 

PROVIDER: E-MTAB-9728 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

altmetric image

Publications

Genes required for aerial growth, cell division, and chromosome segregation are targets of WhiA before sporulation in Streptomyces venezuelae.

Bush Matthew J MJ   Bibb Maureen J MJ   Chandra Govind G   Findlay Kim C KC   Buttner Mark J MJ  

mBio 20130924 5


<h4>Unlabelled</h4>WhiA is a highly unusual transcriptional regulator related to a family of eukaryotic homing endonucleases. WhiA is required for sporulation in the filamentous bacterium Streptomyces, but WhiA homologues of unknown function are also found throughout the Gram-positive bacteria. To better understand the role of WhiA in Streptomyces development and its function as a transcription factor, we identified the WhiA regulon through a combination of chromatin immunoprecipitation-sequenci  ...[more]

Similar Datasets

2021-06-30 | E-MTAB-10631 | biostudies-arrayexpress
2019-07-12 | E-MTAB-8114 | biostudies-arrayexpress
2021-07-01 | E-MTAB-10673 | biostudies-arrayexpress
2021-08-16 | E-MTAB-10818 | biostudies-arrayexpress
2017-11-01 | E-MTAB-5328 | biostudies-arrayexpress
2020-09-30 | E-MTAB-9064 | biostudies-arrayexpress
2016-05-20 | E-MTAB-4673 | biostudies-arrayexpress
2019-01-14 | E-MTAB-7457 | biostudies-arrayexpress
2019-04-24 | E-MTAB-7814 | biostudies-arrayexpress
2021-06-25 | E-MTAB-10648 | biostudies-arrayexpress