The divergent nodes of non-autonomous UPRER signaling through serotonergic and dopaminergic neurons
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ABSTRACT: Performed RNA-seq analysis of animals with xbp-1s overexpression (ER stress response transcription factor) in specific neuron types: pan-neuronal, serotonergic neuron, dopaminergic neuron, and both serotonergic and dopaminergic neurons, all compared to a wild-type control. RNA-seq was performed on purified RNA extracted from ~1000 whole worms using a proprietary Genewiz protocol described briefly in the manuscript. 3 biological replicates are provided for each sample.
INSTRUMENT(S): Illumina HiSeq 4000
ORGANISM(S): Caenorhabditis elegans
SUBMITTER: Ryo Higuchi-Sanabria
PROVIDER: E-MTAB-9771 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
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