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Exome-Seq of murine MB49 cell line - WT and gal-9-KO - in vitro

ABSTRACT: A number of studies have reported evidence of positive or negative contributions of galectin-9 (gal-9) to human and experimental malignancies. Some clinical observations and in vitro experiments suggest that cell-associated gal-9 has anti-metastatic effects. On the other hand, extra-cellular gal-9 consistently enhances tumor immune escape. The aim of this experiment is to study the impact of gal-9 gene invalidation in the murine bladder carcinoma cell line MB49, in vitro. It complements the results of : 1) a RNAseq analysis performed on in vitro cell cultures ; 2) a comparative experiment carried out using the same cells as part of a serial transplantations protocol, whose results are already available on Annotare (E-MTAB-9570 ; E-MTAB-9220).

INSTRUMENT(S): Illumina NovaSeq 6000

ORGANISM(S): Mus musculus

SUBMITTER: Pierre Busson

PROVIDER: E-MTAB-9836 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Exome-Seq of murine CT26 cell line - WT and gal-9-KO - in vitro

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