Ontology highlight
ABSTRACT:
ORGANISM(S): Homo sapiens
SUBMITTER: Gordon Brown
PROVIDER: E-MTAB-987 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Robinson Jessica L L JL Macarthur Stewart S Ross-Innes Caryn S CS Tilley Wayne D WD Neal David E DE Mills Ian G IG Carroll Jason S JS
The EMBO journal 20110624 15
Breast cancer is a heterogeneous disease and several distinct subtypes exist based on differential gene expression patterns. Molecular apocrine tumours were recently identified as an additional subgroup, characterised as oestrogen receptor negative and androgen receptor positive (ER- AR+), but with an expression profile resembling ER+ luminal breast cancer. One possible explanation for the apparent incongruity is that ER gene expression programmes could be recapitulated by AR. Using a cell line ...[more]