Unknown,Transcriptomics,Genomics,Proteomics

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Identification of multiple subclones in Peripheral T-cell Lymphoma, Not Otherwise Specified with genomic aberrations


ABSTRACT: Genomic aberration profiles of Peripheral T-cell Lymphoma, Not Otherwise specified (clinical samples)

ORGANISM(S): Homo sapiens

SUBMITTER: Yoshida Noriaki 

PROVIDER: E-MTAB-998 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Identification of multiple subclones in peripheral T-cell lymphoma, not otherwise specified with genomic aberrations.

Yoshida Noriaki N   Umino Akira A   Liu Fang F   Arita Kotaro K   Karube Kennosuke K   Tsuzuki Shinobu S   Ohshima Koichi K   Seto Masao M  

Cancer medicine 20120926 3


Peripheral T-cell lymphoma, not otherwise specified (PTCL, NOS) with genomic aberrations has been shown to resemble lymphoma-type adult T-cell leukemia/lymphoma (ATLL) in terms of its genomic aberration patterns, histopathology, and prognosis. We have shown recently that a majority of patients with acute-type ATLL have multiple subclones that were likely produced in lymph nodes. In this study, we analyzed whether PTCL, NOS with genomic aberrations also has multiple subclones as found in ATLL by  ...[more]

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