Unknown,Transcriptomics,Genomics,Proteomics

Dataset Information

0

RNA-seq of Dand5 KO and WT mESC


ABSTRACT: DAND5 is an extracellular protein belonging to the family of TGF-β/Nodal signaling antagonists Cerberus/DAN. Loss-of-function of DAND5 in mice leads to a massive increase of the ventricular heart wall’s thickness caused by an increased mitotic index of the CMs at the compact myocardium. To clarify the function of DAND5 in the molecular control of cardiomyogenesis, we carried out RNA-seq of a Dand5 KO mouse embryonic stem cell line (mESC) that proved to be a valuable in vitro cardiac differentiation model.

INSTRUMENT(S): Illumina NovaSeq 6000

ORGANISM(S): Mus musculus

SUBMITTER: Matthias Futschik 

PROVIDER: E-MTAB-9986 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

Similar Datasets

2009-03-15 | E-GEOD-10970 | biostudies-arrayexpress
2009-09-12 | E-GEOD-17513 | biostudies-arrayexpress
2010-05-12 | E-TABM-716 | biostudies-arrayexpress
2018-12-07 | PXD011518 | Pride
2023-09-02 | PXD043836 | Pride
2023-02-01 | E-MTAB-10491 | biostudies-arrayexpress
2013-12-10 | E-GEOD-53106 | biostudies-arrayexpress
2017-07-23 | E-MTAB-4978 | biostudies-arrayexpress
2013-02-05 | E-GEOD-36679 | biostudies-arrayexpress
2013-12-10 | E-GEOD-53108 | biostudies-arrayexpress