Metabolomics,Unknown,Transcriptomics,Genomics,Proteomics

Dataset Information

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Transcription profiling of yeast timecourses with nutrient limiting conditions S= sulfate, P=phosphate, U=uracil, L=leucine


ABSTRACT: This data file contains all the data used to produce Figure 4 of Saldanha, Brauer and Bostein. The limiting nutrient is indicated by the letter followed by the timecourse number. S= sulfate, P=phosphate, U=uracil, L=leucine. The chemostat comparisons are prefixed by CC. Channels are as noted in the individual arrays, and are consistent for a given timecouse, but may vary between time courses.

ORGANISM(S): Saccharomyces cerevisiae

SUBMITTER: Alok Saldanha 

PROVIDER: E-SMDB-2655 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Publications

Nutritional homeostasis in batch and steady-state culture of yeast.

Saldanha Alok J AJ   Brauer Matthew J MJ   Botstein David D  

Molecular biology of the cell 20040707 9


We studied the physiological response to limitation by diverse nutrients in batch and steady-state (chemostat) cultures of S. cerevisiae. We found that the global pattern of transcription in steady-state cultures in limiting phosphate or sulfate is essentially identical to that of batch cultures growing in the same medium just before the limiting nutrient is completely exhausted. The massive stress response and complete arrest of the cell cycle that occurs when nutrients are fully exhausted in b  ...[more]

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