Ontology highlight
ABSTRACT:
ORGANISM(S): Homo sapiens
SUBMITTER: Michael Griffiths
PROVIDER: E-SMDB-2669 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Griffiths Michael J MJ Shafi Mohammed J MJ Popper Stephen J SJ Hemingway Cheryl A CA Kortok Moses M MM Wathen Andrew A Rockett Kirk A KA Mott Richard R Levin Michael M Newton Charles R CR Marsh Kevin K Relman David A DA Kwiatkowski Dominic P DP
The Journal of infectious diseases 20050414 10
Malaria is a global problem, and there is a critical need for further understanding of the disease process. When malarial parasites invade and develop within the bloodstream, they stimulate a profound host response whose main clinical sign is fever. To explore this response, we measured host gene expression in whole blood from Kenyan children hospitalized with either acute malaria or other febrile illnesses. Genomewide analysis of expression identified 2 principal gene-expression profiles relate ...[more]