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Transcription profiling of cohort of human cutaneous primary melanomas associated with a distant metastasis free survival

ABSTRACT: Identification of genomic characteristics in a cohorte of human cutaneous primary melanoma associated with a distant metastasis free survival.

ORGANISM(S): Homo sapiens

SUBMITTER: Philippe Dessen

PROVIDER: E-TABM-1 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Gene expression profiling of primary cutaneous melanoma and clinical outcome.

Winnepenninckx Véronique V Lazar Vladimir V Michiels Stefan S Dessen Philippe P Stas Marguerite M Alonso Soledad R SR Avril Marie-Françoise MF Ortiz Romero Pablo L PL Robert Thomas T Balacescu Ovidiu O Eggermont Alexander M M AM Lenoir Gilbert G Sarasin Alain A Tursz Thomas T van den Oord Joost J JJ Spatz Alain A

Journal of the National Cancer Institute 20060401 7

<h4>Background</h4>Gene expression profiling data for human primary cutaneous melanomas are scarce because of the lack of retrospective collections of frozen tumors. To identify differentially expressed genes that may be involved in melanoma progression and prognosis, we investigated the relationship between gene expression profiles and clinical outcome in a cohort of patients with primary melanoma.<h4>Methods</h4>Labeled complementary RNA (cRNA) from each tissue sample was hybridized to a pange ...[more]

PMID: 16595783

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