Ontology highlight
ABSTRACT:
ORGANISM(S): Mus musculus
SUBMITTER: Jeroen Pennings
PROVIDER: E-TABM-1094 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Pennings Jeroen L A JL Schuurhof Annemieke A Hodemaekers Hennie M HM Buisman Annemarie A de Rond Lia C G H LC Widjojoatmodjo Myra N MN Luytjes Willem W Kimpen Jan L L JL Bont Louis L Janssen Riny R
PloS one 20110624 6
Respiratory Syncytial Virus is a frequent cause of severe bronchiolitis in children. To improve our understanding of systemic host responses to RSV, we compared BALB/c mouse gene expression responses at day 1, 2, and 5 during primary RSV infection in lung, bronchial lymph nodes, and blood. We identified a set of 53 interferon-associated and innate immunity genes that give correlated responses in all three murine tissues. Additionally, we identified blood gene signatures that are indicative of ac ...[more]