Unknown,Transcriptomics,Genomics,Proteomics

Dataset Information

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HeLa cell cycle time series


ABSTRACT:

ORGANISM(S): Homo sapiens

SUBMITTER: Einar Ryeng 

PROVIDER: E-TABM-1152 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Publications

Transcription profiling during the cell cycle shows that a subset of Polycomb-targeted genes is upregulated during DNA replication.

Peña-Diaz Javier J   Hegre Siv A SA   Anderssen Endre E   Aas Per A PA   Mjelle Robin R   Gilfillan Gregor D GD   Lyle Robert R   Drabløs Finn F   Krokan Hans E HE   Sætrom Pål P  

Nucleic acids research 20130115 5


Genome-wide gene expression analyses of the human somatic cell cycle have indicated that the set of cycling genes differ between primary and cancer cells. By identifying genes that have cell cycle dependent expression in HaCaT human keratinocytes and comparing these with previously identified cell cycle genes, we have identified three distinct groups of cell cycle genes. First, housekeeping genes enriched for known cell cycle functions; second, cell type-specific genes enriched for HaCaT-specifi  ...[more]

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