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Unknown,Transcriptomics,Genomics,Proteomics

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Transcription profiling of human breast cancer samples

ABSTRACT: We measured baseline gene expression profiles for a set of breast tumors. Note: this experiment was modified in June 2008 when the CEL files associated with some hybridizations were changed.

ORGANISM(S): Homo sapiens

SUBMITTER: paul spellman

PROVIDER: E-TABM-158 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Publications

Gene expression profile analysis of t1 and t2 breast cancer reveals different activation pathways.

Riis Margit L H ML Zhao Xi X Kaveh Fateme F Vollan Hilde S HS Nesbakken Anne-Jorunn AJ Solvang Hiroko K HK Lüders Torben T Bukholm Ida R K IR Kristensen Vessela N VN

ISRN oncology 20130228

Breast cancers today are of predominantly T1 (0.1 ≥ 2.0 cm) or T2 (>2 ≤ 5 cm) categories due to early diagnosis. Molecular profiling using microarrays has led to the notion of breast cancer as a heterogeneous disease both clinically and molecularly. Given the prognostic power and clinical use of tumor size, the purpose of this study was to search for molecular signatures characterizing clinical T1 and T2. In total 46 samples were included in the discovery dataset. After adjusting for hormone rec ...[more]

PMID: 23533813

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