Ontology highlight
ABSTRACT:
ORGANISM(S): Arabidopsis thaliana
SUBMITTER: Michael Gardner
PROVIDER: E-TABM-331 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Dodd Antony N AN Gardner Michael J MJ Hotta Carlos T CT Hubbard Katharine E KE Dalchau Neil N Love John J Assie Jean-Maurice JM Robertson Fiona C FC Jakobsen Mia Kyed MK Gonçalves Jorge J Sanders Dale D Webb Alex A R AA
Science (New York, N.Y.) 20071115 5857
Transcriptional feedback loops are a feature of circadian clocks in both animals and plants. We show that the plant circadian clock also incorporates the cytosolic signaling molecule cyclic adenosine diphosphate ribose (cADPR). cADPR modulates the circadian oscillator's transcriptional feedback loops and drives circadian oscillations of Ca2+ release. The effects of antagonists of cADPR signaling, manipulation of cADPR synthesis, and mathematical simulation of the interaction of cADPR with the ci ...[more]