Ontology highlight
ABSTRACT:
ORGANISM(S): Saccharomyces cerevisiae
SUBMITTER: Jakub Orzechowski Westholm
PROVIDER: E-TABM-448 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Westholm Jakub Orzechowski JO Nordberg Niklas N Murén Eva E Ameur Adam A Komorowski Jan J Ronne Hans H
BMC genomics 20081216
<h4>Background</h4>Expression of a large number of yeast genes is repressed by glucose. The zinc finger protein Mig1 is the main effector in glucose repression, but yeast also has two related proteins: Mig2 and Mig3. We have used microarrays to study global gene expression in all possible combinations of mig1, mig2 and mig3 deletion mutants.<h4>Results</h4>Mig1 and Mig2 repress a largely overlapping set of genes on 2% glucose. Genes that are upregulated in a mig1 mig2 double mutant were grouped ...[more]