Unknown,Transcriptomics,Genomics,Proteomics

Dataset Information

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Transcription profiling of human breast epithelial tissue


ABSTRACT:

ORGANISM(S): Homo sapiens

SUBMITTER: Anita Grigoriadis 

PROVIDER: E-TABM-657 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Publications

Identification of differentially expressed sense and antisense transcript pairs in breast epithelial tissues.

Grigoriadis Anita A   Oliver Gavin R GR   Tanney Austin A   Kendrick Howard H   Smalley Matt J MJ   Jat Parmjit P   Neville A Munro AM  

BMC genomics 20090717


<h4>Background</h4>More than 20% of human transcripts have naturally occurring antisense products (or natural antisense transcripts--NATs), some of which may play a key role in a range of human diseases. To date, several databases of in silico defined human sense-antisense (SAS) pairs have appeared, however no study has focused on differential expression of SAS pairs in breast tissue. We therefore investigated the expression levels of sense and antisense transcripts in normal and malignant human  ...[more]

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