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Metabolomics,Unknown,Transcriptomics,Genomics,Proteomics

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Comparative genomic hybridization of human glioblastomas

ABSTRACT: A Cartes d'Identite des Tumeurs (CIT) project from the french Ligue Nationale Contre le Cancer (http://cit.ligue-cancer.net ) | Human genome-wide CIT-aCGH-V6-4.4K : 67 glioblastomas | Submitter : Aurelien de Reynies | Project leader : Francois Berger

ORGANISM(S): Homo sapiens

SUBMITTER: Aurelien de Reynies

PROVIDER: E-TABM-897 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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An ANOCEF genomic and transcriptomic microarray study of the response to radiotherapy or to alkylating first-line chemotherapy in glioblastoma patients.

Ducray François F de Reyniès Aurélien A Chinot Olivier O Idbaih Ahmed A Figarella-Branger Dominique D Colin Carole C Karayan-Tapon Lucie L Chneiweiss Hervé H Wager Michel M Vallette François F Marie Yannick Y Rickman David D Thomas Emilie E Delattre Jean-Yves JY Honnorat Jérôme J Sanson Marc M Berger François F

Molecular cancer 20100907

<h4>Background</h4>The molecular characteristics associated with the response to treatment in glioblastomas (GBMs) remain largely unknown. We performed a retrospective study to assess the genomic characteristics associated with the response of GBMs to either first-line chemotherapy or radiation therapy. The gene expression (n = 56) and genomic profiles (n = 67) of responders and non-responders to first-line chemotherapy or radiation therapy alone were compared on Affymetrix Plus 2 gene expressio ...[more]

PMID: 20822523

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Comparative genomic hybridization of human nasal NK/T-cell Lymphoma (8 tumor samples, 2 cell lines)

Project description:A ï¾Cartes dï¾Identite des Tumeursï¾ (CIT) project from the french Ligue Nationale Contre le Cancer (http://cit.ligue-cancer.net ) | Human genome-wide CIT-aCGH-V6-4.4K : 8 NKTCL biopsies, 2 NKTCL cell lines. Biopsies and cell lines of NK/T-cell lymphoma, nasal-type (NKTCL) were subject to combined gene expression profiling (see E-TABM-702) and array-based comparative genomic hybridization analyses. | Submitter : Aurelien de Reynies <reyniesa@ligue-cancer.fr> | Project leader : Philippe Gaulard <philippe.gaulard@hmn.aphp.fr>

2009-12-31 | E-TABM-791 | biostudies-arrayexpress

Expression and CGHarray profiling of Hepatosplenic T-cell Lymphomas (10 tumor samples)

Project description:A Cartes dIdentite des Tumeurs (CIT) project from the french Ligue Nationale Contre le Cancer (http://cit.ligue-cancer.net) | Affymetrix HG-U133 Plus 2.0 : 10 HSTL samples including biopsies (n=6), sorted tumor cells (n=3), cell line (n=1) | Agilent SurePrint G3 Human CGH Microarray 4x180K Arrays : 7 HSTL samples including biopsies (n=5), sorted tumor cells (n=1), cell line (n=1) | Submitter : Aurelien de Reynies <reyniesa@ligue-cancer.fr> | Project leader : Philippe Gaulard <philippe.gaulard@hmn.aphp.fr> The E-MTAB-638.additional.1.zip archive contains the CGH processed data file with additional chromosome coordiantes.

2011-09-30 | E-MTAB-638 | biostudies-arrayexpress

Expression and CGH array profiling of ductal carcinoma (135 tumor samples)

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2012-02-01 | E-MTAB-748 | biostudies-arrayexpress

Gene expression Classification of Colon Cancer defines six molecular subtypes with distinct clinical, molecular and survival characteristics [CGH]

Project description:From a clinical and molecular perspective, colon cancer (CC) is a heterogeneous disease but to date no classification based on high-density transcriptome data has been established. The aim of this study was to build up a robust molecular classification ofÂ mRNA expression profiles (Affymetrix U133Plus2) ofÂ a large series of 443 CC and to validate it on an independent serie of 123 CC and 906 public dataset.Â We identified and validated six molecular subtypes in this large cohort as a combination of multiple molecular processes that complement current disease stratification based on clinicopathological variables and molecular markers. The biological relevance of these subtypes was consolidated by significant differences in survival. These insights open new perspectives for improving prognostic models and targeted therapies. Among a large series of colon cancers collected for the Cartes d'IdentitÃ© des Tumeurs (CIT) program from the French Ligue Nationale Contre le Cancer (http://cit.ligue-cancer.net), 566 were analyzed for mRNA expression profiles using Affymetrix U133plus2 chip and, among theses, 463 could also be analyzed for DNA alteration profiles using the CGH Array (Â CIT-CGHarray V6). The 566 tumors was divided into a discovery dataset of 443 CC and a validation dataset of 123 CC.

2013-05-22 | E-GEOD-40966 | biostudies-arrayexpress

Gene expression Classification of Colon Cancer defines six molecular subtypes with distinct clinical, molecular and survival characteristics

Project description:This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

2013-05-22 | E-GEOD-40967 | biostudies-arrayexpress

Comparative genomic hybridization of 84 head and neck squamous cell carcinoma

Project description:A ﾑCartes dﾒIdentite des Tumeursﾒ (CIT) project from the french Ligue Nationale Contre le Cancer (http://cit.ligue-cancer.net ) | Human genome-wide CIT-aCGH-V7-4.7K : 84 HNSCC | Submitter : Aurelien de Reynies <reyniesa@ligue-cancer.fr> | Project leader : Bohdan Wazylyk <boh@igbmc.fr>

2010-05-15 | E-TABM-995 | biostudies-arrayexpress

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2011-04-18 | E-MTAB-659 | biostudies-arrayexpress

Genotyping of Malignant Pleural Mesothelioma primary cell lines by SNP array

Project description:SNP array data from 45 cell lines of Malignant Pleural Mesothelioma were used to explore recurrent copy number alterations. This study was part of Cartes d'Identité des Tumeurs (CIT) project from the french Ligue Nationale Contre le Cancer.

2023-12-31 | GSE197288 | GEO

DNA methylation profiling in pheochromocytoma and paraganglioma reveals diagnostic and prognostic markers

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2015-05-11 | GSE62082 | GEO

Transcription profiling of human ductal and lobular breast cancers with familial or Cowden disease history.

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