Decoy Receptors Regulation by Resveratrol in Lipopolysaccharide-Activated Microglia.
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ABSTRACT:
SUBMITTER: Calvello R
PROVIDER: S-EPMC10000713 | biostudies-literature | 2023 Feb
REPOSITORIES: biostudies-literature
Publications
Decoy Receptors Regulation by Resveratrol in Lipopolysaccharide-Activated Microglia.
Calvello Rosa R Porro Chiara C Lofrumento Dario Domenico DD Ruggiero Melania M Panaro Maria Antonietta MA Cianciulli Antonia A
Cells 20230221 5
Resveratrol is a polyphenol that acts as antioxidants do, protecting the body against diseases, such as diabetes, cancer, heart disease, and neurodegenerative disorders, such as Alzheimer's (AD) and Parkinson's diseases (PD). In the present study, we report that the treatment of activated microglia with resveratrol after prolonged exposure to lipopolysaccharide is not only able to modulate pro-inflammatory responses, but it also up-regulates the expression of decoy receptors, IL-1R2 and ACKR2 (a ...[more]
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