Ontology highlight
ABSTRACT:
SUBMITTER: Pankratz F
PROVIDER: S-EPMC10002482 | biostudies-literature | 2023 Mar
REPOSITORIES: biostudies-literature
Pankratz Franziska F Maksudova Aziza A Goesele Roman R Meier Lena L Proelss Kora K Marenne Katia K Thut Ann-Kathrin AK Sengle Gerhard G Correns Annkatrin A Begelspacher Jeanina J Alkis Deniz D Siegel Patrick M PM Smolka Christian C Grundmann Sebastian S Moser Martin M Zhou Qian Q Esser Jennifer S JS
International journal of molecular sciences 20230303 5
Dedifferentiated vascular smooth muscle cells (vSMCs) play an essential role in neointima formation, and we now aim to investigate the role of the bone morphogenetic protein (BMP) modulator BMPER (BMP endothelial cell precursor-derived regulator) in neointima formation. To assess BMPER expression in arterial restenosis, we used a mouse carotid ligation model with perivascular cuff placement. Overall BMPER expression after vessel injury was increased; however, expression in the tunica media was d ...[more]