Ct, IL-18 polymorphism, and laboratory biomarkers for predicting chemosensory dysfunctions and mortality in COVID-19.
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ABSTRACT: Aim
Patients with COVID-19 often experience chemosensory dysfunction. This research intends to uncover the association of RT-PCR Ct value with chemosensory dysfunctions and SpO2. This study also aims to investigate Ct, SpO2, CRP, D-dimer, and -607 IL-18 T/G polymorphism in order to find out predictors of chemosensory dysfunctions and mortality.Materials & methods
This study included 120 COVID-19 patients, of which 54 were mild, 40 were severe and 26 were critical. CRP, D-dimer, RT-PCR, and IL-18 polymorphism were evaluated. Results & conclusion: Low Ct was associated with SpO2 dropping and chemosensory dysfunctions. IL-18 T/G polymorphism did not show an association with COVID-19 mortality; conversely, age, BMI, D-dimer and Ct values did.
SUBMITTER: Smail SW
PROVIDER: S-EPMC10005086 | biostudies-literature | 2023 Feb
REPOSITORIES: biostudies-literature
Publications
Ct, <i>IL-18</i> polymorphism, and laboratory biomarkers for predicting chemosensory dysfunctions and mortality in COVID-19.
Smail Shukur Wasman SW Babaei Esmaeil E Amin Kawa K
Future science OA 20230201 2
<h4>Aim</h4>Patients with COVID-19 often experience chemosensory dysfunction. This research intends to uncover the association of RT-PCR Ct value with chemosensory dysfunctions and SpO<sub>2</sub>. This study also aims to investigate Ct, SpO<sub>2</sub>, CRP, D-dimer, and -607 <i>IL-18</i> T/G polymorphism in order to find out predictors of chemosensory dysfunctions and mortality.<h4>Materials & methods</h4>This study included 120 COVID-19 patients, of which 54 were mild, 40 were severe and 26 w ...[more]
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