Ontology highlight
ABSTRACT:
SUBMITTER: Jeong S
PROVIDER: S-EPMC10005277 | biostudies-literature | 2023 Mar
REPOSITORIES: biostudies-literature
Jeong Sohyeon S Kang Hyun Wook HW Kim So Hyun SH Hong Gyu-Sang GS Nam Min-Ho MH Seong Jihye J Yoon Eui-Sung ES Cho Il-Joo IJ Chung Seok S Bang Seokyoung S Kim Hong Nam HN Choi Nakwon N
Science advances 20230310 10
Anisotropically organized neural networks are indispensable routes for functional connectivity in the brain, which remains largely unknown. While prevailing animal models require additional preparation and stimulation-applying devices and have exhibited limited capabilities regarding localized stimulation, no in vitro platform exists that permits spatiotemporal control of chemo-stimulation in anisotropic three-dimensional (3D) neural networks. We present the integration of microchannels seamless ...[more]