Ontology highlight
ABSTRACT:
SUBMITTER: Lu X
PROVIDER: S-EPMC10008190 | biostudies-literature | 2023
REPOSITORIES: biostudies-literature
Lu Xiaolong X Chen Yang Y Zhang Gong G
Computational and structural biotechnology journal 20230312
The SARS-CoV-2 virus, which causes the COVID-19, is rapidly accumulating mutations to adapt to the hosts. We collected SARS-CoV-2 sequence data from the end of 2019 to January 2023 to analyze for their evolutionary features during the pandemic. We found that most of the SARS-CoV-2 genes are undergoing negative purifying selection, while the spike protein gene (S-gene) is undergoing rapid positive selection. From the original strain to the alpha, delta and omicron variant types, the Ka/Ks of the ...[more]