Ontology highlight
ABSTRACT:
SUBMITTER: Fukunaka A
PROVIDER: S-EPMC10017767 | biostudies-literature | 2023 Mar
REPOSITORIES: biostudies-literature
Fukunaka Ayako A Shimura Mari M Ichinose Takayuki T Pereye Ofejiro B OB Nakagawa Yuko Y Tamura Yasuko Y Mizutani Wakana W Inoue Ryota R Inoue Takato T Tanaka Yuto Y Sato Takashi T Saitoh Tatsuya T Fukada Toshiyuki T Nishida Yuya Y Miyatsuka Takeshi T Shirakawa Jun J Watada Hirotaka H Matsuyama Satoshi S Fujitani Yoshio Y
Scientific reports 20230315 1
Metal homeostasis is tightly regulated in cells and organisms, and its disturbance is frequently observed in some diseases such as neurodegenerative diseases and metabolic disorders. Previous studies suggest that zinc and iron are necessary for the normal functions of pancreatic β cells. However, the distribution of elements in normal conditions and the pathophysiological significance of dysregulated elements in the islet in diabetic conditions have remained unclear. In this study, to investigat ...[more]