Ontology highlight
ABSTRACT:
SUBMITTER: Frydman GH
PROVIDER: S-EPMC10019826 | biostudies-literature | 2023
REPOSITORIES: biostudies-literature
Frydman Galit H GH Ellett Felix F Jorgensen Julianne J Marand Anika L AL Zukerberg Lawrence L Selig Martin K MK Tessier Shannon N SN Wong Keith H K KHK Olaleye David D Vanderburg Charles R CR Fox James G JG Tompkins Ronald G RG Irimia Daniel D
Frontiers in immunology 20230302
Megakaryocytes (MKs) are precursors to platelets, the second most abundant cells in the peripheral circulation. However, while platelets are known to participate in immune responses and play significant functions during infections, the role of MKs within the immune system remains largely unexplored. Histological studies of sepsis patients identified increased nucleated CD61<sup>+</sup> cells (MKs) in the lungs, and CD61<sup>+</sup> staining (likely platelets within microthrombi) in the kidneys, ...[more]