Ontology highlight
ABSTRACT:
SUBMITTER: Shi D
PROVIDER: S-EPMC10025115 | biostudies-literature | 2023 Mar
REPOSITORIES: biostudies-literature
Shi Dafa D Ren Zhendong Z Zhang Haoran H Wang Guangsong G Guo Qiu Q Wang Siyuan S Ding Jie J Yao Xiang X Li Yanfei Y Ren Ke K
Heliyon 20230306 3
Parkinson's disease (PD) is a highly heterogeneous disorder that is difficult to diagnose. Therefore, reliable biomarkers are needed. We implemented a method constructing a regional radiomics similarity network (R2SN) based on the amplitude of low-frequency fluctuation (ALFF). We classified patients with PD and healthy individuals by using a machine learning approach in accordance with the R2SN connectome. The ALFF-based R2SN exhibited great reproducibility with different brain atlases and datas ...[more]