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Manganese(I)-Catalyzed Asymmetric Hydrophosphination of α,β-Unsaturated Carbonyl Derivatives.

ABSTRACT: Here we report catalytic asymmetric hydrophosphination of α,β-unsaturated carbonyl derivatives using a chiral Mn(I) complex as a catalyst. Through H-P bond activation, various phosphine-containing chiral products can be accessed via hydrophosphination of various ketone-, ester-, and carboxamide-based Michael acceptors.

SUBMITTER: Postolache R

PROVIDER: S-EPMC10028696 | biostudies-literature | 2023 Mar

REPOSITORIES: biostudies-literature

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Manganese(I)-Catalyzed Asymmetric Hydrophosphination of α,β-Unsaturated Carbonyl Derivatives.

Postolache Roxana R Pérez Juana M JM Castiñeira Reis Marta M Ge Luo L Sinnema Esther G EG Harutyunyan Syuzanna R SR

Organic letters 20230309 10

Here we report catalytic asymmetric hydrophosphination of α,β-unsaturated carbonyl derivatives using a chiral Mn(I) complex as a catalyst. Through H-P bond activation, various phosphine-containing chiral products can be accessed via hydrophosphination of various ketone-, ester-, and carboxamide-based Michael acceptors. ...[more]

PMID: 36892214

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