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Minimal and normal-flow general anesthesia in patients undergoing surgery in prone position: ımpact on hemodynamics and regional cerebral oxygenation.


ABSTRACT:

Purpose

In this study, the aim to assess the combined effects of prone-positioning (PP) and minimal-flow (MF) general anesthesia on regional cerebral oxygenation (RCO) and systemic hemodynamics.

Methods

This is a randomized prospective study aiming to evaluate changes in cerebral oxygenation and hemodynamic parameters in MF systemic anesthesia in patients undergoing surgery in PP. Patients were randomized to MF or normal-flow (NF) anesthesia. In the operating room, pulse rate, mean arterial pressure (MAP), peripheral hemoglobin oxygen saturation (spO2), and right- and left-side RCO (assessed by near-infrared spectroscopy, NIRS) were measured perioperatively.

Results

Overall, 46 patients were included (24 in the MF group and 22 in the NF group). The amount of anesthetic gas consumption was significantly lower in the low-flow (LF) group. In both groups, the mean pulse rate showed a decrease after PP. Before induction, RCO was significantly higher both at the right- and left-sides in the LF group compared to the NF group. This difference continued throughout the operation on the left-side and disappeared 10 min after intubation on the right-side. On the left side, mean RCO decreased after PP in both groups.

Conclusions

MF anesthesia in PP did not reduce cerebral oxygenation compared to NF and was safe in terms of systemic hemodynamics and cerebral oxygenation.

SUBMITTER: Tekin EA 

PROVIDER: S-EPMC10042492 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature

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Publications

Minimal and normal-flow general anesthesia in patients undergoing surgery in prone position: ımpact on hemodynamics and regional cerebral oxygenation.

Tekin Esra Akdaş EA   Gültop Fethi F   Başkurt Nihan Altıntepe NA  

Acta cirurgica brasileira 20230324


<h4>Purpose</h4>In this study, the aim to assess the combined effects of prone-positioning (PP) and minimal-flow (MF) general anesthesia on regional cerebral oxygenation (RCO) and systemic hemodynamics.<h4>Methods</h4>This is a randomized prospective study aiming to evaluate changes in cerebral oxygenation and hemodynamic parameters in MF systemic anesthesia in patients undergoing surgery in PP. Patients were randomized to MF or normal-flow (NF) anesthesia. In the operating room, pulse rate, mea  ...[more]

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