Ontology highlight
ABSTRACT:
SUBMITTER: Jeong TH
PROVIDER: S-EPMC10053066 | biostudies-literature | 2023 Mar
REPOSITORIES: biostudies-literature
Jeong Tae-Hwan TH Hong Hye-Won HW Kim Min Soo MS Song Miryoung M Myung Heejoon H
Viruses 20230304 3
Genes encoding endolysins were identified and cloned from three different <i>Escherichia coli</i> bacteriophages, 10-24(13), PBEC30, and PBEC56. Putative antimicrobial peptide (AMP)-like C-terminal alpha helix structures with amphipathic natures were predicted from the three endolysins. Each gene was cloned and expressed as hexahistidine-tagged forms, and the products were purified and characterized. The purified endolysins exhibited antibacterial activities against a variety of Gram-negative ba ...[more]