Ontology highlight
ABSTRACT:
SUBMITTER: Elbezanti WO
PROVIDER: S-EPMC10056051 | biostudies-literature | 2023 Mar
REPOSITORIES: biostudies-literature
Elbezanti Weam Othman WO Challagundla Kishore B KB Jonnalagadda Subash C SC Budak-Alpdogan Tulin T Pandey Manoj K MK
Pharmaceuticals (Basel, Switzerland) 20230308 3
Multiple myeloma (MM) is a challenging hematological cancer which typically grows in bone marrow. MM accounts for 10% of hematological malignancies and 1.8% of cancers. The recent treatment strategies have significantly improved progression-free survival for MM patients in the last decade; however, a relapse for most MM patients is inevitable. In this review we discuss current treatment, important pathways for proliferation, survival, immune suppression, and resistance that could be targeted for ...[more]