Ontology highlight
ABSTRACT:
SUBMITTER: Furuta H
PROVIDER: S-EPMC10067742 | biostudies-literature | 2023
REPOSITORIES: biostudies-literature
Furuta Haruka H Yamada Mari M Nagashima Takuya T Matsuda Shuichi S Nagayasu Kazuki K Shirakawa Hisashi H Kaneko Shuji S
Frontiers in pharmacology 20230320
Tendinopathy, a degenerative disease, is characterized by pain, loss of tendon strength, or rupture. Previous studies have identified multiple risk factors for tendinopathy, including aging and fluoroquinolone use; however, its therapeutic target remains unclear. We analyzed self-reported adverse events and the US commercial claims data and found that the short-term use of dexamethasone prevented both fluoroquinolone-induced and age-related tendinopathy. Rat tendons treated systemically with flu ...[more]