Dataset Information
DeepPheWAS: an R package for phenotype generation and association analysis for phenome-wide association studies.
Ontology highlight
ABSTRACT: Summary
DeepPheWAS is an R package for phenome-wide association studies that creates clinically curated composite phenotypes and integrates quantitative phenotypes from primary care data, longitudinal trajectories of quantitative measures, disease progression and drug response phenotypes. Tools are provided for efficient analysis of association with any genetic input, under any genetic model, with optional sex-stratified analysis, and for developing novel phenotypes.Availability and implementation
The DeepPheWAS R package is freely available under GNU general public licence v3.0 from at https://github.com/Richard-Packer/DeepPheWAS.Supplementary information
Supplementary data are available at Bioinformatics online.
SUBMITTER: Packer RJ
PROVIDER: S-EPMC10070035 | biostudies-literature | 2023 Apr
REPOSITORIES: biostudies-literature
Publications
DeepPheWAS: an R package for phenotype generation and association analysis for phenome-wide association studies.
Bioinformatics (Oxford, England) 20230401 4
<h4>Summary</h4>DeepPheWAS is an R package for phenome-wide association studies that creates clinically curated composite phenotypes and integrates quantitative phenotypes from primary care data, longitudinal trajectories of quantitative measures, disease progression and drug response phenotypes. Tools are provided for efficient analysis of association with any genetic input, under any genetic model, with optional sex-stratified analysis, and for developing novel phenotypes.<h4>Availability and ...[more]