Ontology highlight
ABSTRACT:
SUBMITTER: Cheng L
PROVIDER: S-EPMC10076011 | biostudies-literature | 2023
REPOSITORIES: biostudies-literature
Cheng Liqin L Liu Tingting T Liu Qiongg Q Lian Liming L Tang Guosheng G Mille Luis Santiago LS García Fabricio Romero FR Engstrand Lars L Zhang Yu Shrike YS Du Juan J
Research (Washington, D.C.) 20230227
The role of the human intestinal tract in host-microbe interactions has been highlighted in recent years. Several 3-dimensional (3D) models have been developed to reproduce the physiological characteristics of the human gut and to investigate the function of the gut microbiota. One challenge for 3D models is to recapitulate the low oxygen concentrations in the intestinal lumen. Moreover, most earlier 3D culture systems used a membrane to physically separate bacteria from the intestinal epitheliu ...[more]